摘要：俗话说，不谈剂量谈危害都是耍流氓，网络上有很多咖啡危害辟谣的文章，完全忽视咖啡的摄入量而大谈特谈咖啡无害。然而，现代人几乎都离不开咖啡，有很多人群都喜欢喝高浓度咖啡，再加上日常喝茶，以及碳酸饮料中的咖啡因，已经有越来越多的人群，面临咖啡因的长期过量摄入。在不知
原创 较高端人类 较高端人类
【写在最后】俗话说，不谈剂量谈危害都是耍流氓，网络上有很多咖啡危害辟谣的文章，完全忽视咖啡的摄入量而大谈特谈咖啡无害。然而，现代人几乎都离不开咖啡，有很多人群都喜欢喝高浓度咖啡，再加上日常喝茶，以及碳酸饮料中的咖啡因，已经有越来越多的人群，面临咖啡因的长期过量摄入。在不知不觉中，咖啡因已经对它们的身体造成威胁。尤其是对于一些本身存在胃病、肝脏代谢疾病，以及免疫力低下的人群，身体受到的危害可能已经越来越严重。当咖啡被塑造成绝对无害时，这类人群便很容易忽视咖啡因对他们造成的危害，从而饮用咖啡时更加的没有节制，从而让身体健康面临更大的威胁。咖啡本身是一把双刃剑，当你适度饮用时，它会有益于你的健康。但如果你过度饮用，反而会危害你的健康。参考资料[1] Zivković R. Coffee and health in the elderly. Acta Med Croatica. 2000;54(1):33-6. PMID: 10914439.[2] Raaska K, Raitasuo V, Laitila J, Neuvonen PJ. Effect of caffeine-containing versus decaffeinated coffee on serum clozapine concentrations in hospitalised patients. Basic Clin Pharmacol Toxicol. 2004 Jan;94(1):13-8. PMID: 14725610.[3] Crozier TW, Stalmach A, Lean ME, Crozier A. Espresso coffees, caffeine and chlorogenic acid intake: potential health implications. Food Funct. 2012 Jan;3(1):30-3. doi: 10.1039/c1fo10240k. Epub 2011 Nov 30. PMID: 22130653.[4] Ludwig IA, Mena P, Calani L, Cid C, Del Rio D, Lean ME, Crozier A. Variations in caffeine and chlorogenic acid contents of coffees: what are we drinking? Food Funct. 2014 Aug;5(8):1718-26. doi: 10.1039/c4fo00290c. PMID: 25014672.[5] Silletta MG, Marchioli R. Caffè rischio di malattie cardiovascolari: yin e yang [Coffee and cardiovascular disease risk: yin and yang]. Recenti Prog Med. 2008 Nov;99(11):533-7. Italian. PMID: 19209536.[6] Glover FE, Caudle WM, Del Giudice F, Belladelli F, Mulloy E, Lawal E, Eisenberg ML. The association between caffeine intake and testosterone: NHANES 2013-2014. Nutr J. 2022 May 17;21(1):33. doi: 10.1186/s12937-022-00783-z. PMID: 35578259; PMCID: PMC9112543.[7] Paz-Graniel I, Kose J, Babio N, Hercberg S, Galan P, Touvier M, Salas-Salvadó J, Andreeva VA. Caffeine Intake and Its Sex-Specific Association with General [8] Anxiety: A Cross-Sectional Analysis among General Population Adults. Nutrients. 2022 Mar 15;14(6):1242. doi: 10.3390/nu14061242. PMID: 35334898; PMCID: PMC8951500.[9] Zhang WZ, Sun NN, Hu Y, Cao Y, Amber S. Caffeine Exposure Causes Immune Dysfunction and Intrauterine Growth Restriction Retardation in Rats. Biomed Environ Sci. 2022 Feb 20;35(2):170-173. doi: 10.3967/bes2022.025. PMID: 35197185.[10] Fortier I, Marcoux S, Beaulac-Baillargeon L. Relation of caffeine intake during pregnancy to intrauterine growth retardation and preterm birth. Am J Epidemiol. 1993 May 1;137(9):931-40. doi: 10.1093/oxfordjournals.aje.a116763. PMID: 8317450.[11] Purdue-Smithe AC, Kim K, Schliep KC, DeVilbiss EA, Hinkle SN, Ye A, Perkins NJ, Sjaarda LA, Silver RM, Schisterman EF, Mumford SL. Preconception caffeine metabolites, caffeinated beverage intake, and fecundability. Am J Clin Nutr. 2022 Apr 1;115(4):1227-1236. doi: 10.1093/ajcn/nqab435. PMID: 35030239; PMCID: PMC8970989.[12] Poole R, Kennedy OJ, Roderick P, Fallowfield JA, Hayes PC, Parkes J. Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes. BMJ. 2017 Nov 22;359:j5024. doi: 10.1136/bmj.j5024. Erratum in: BMJ. 2018 Jan 12;360:k194. PMID: 29167102; PMCID: PMC5696634. 来源：健康10点
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