tanezumab

Tanezumab，880266-57-9，人源化IgG2型单克隆抗体

Tanezumab（他尼珠单抗）是一种人源化IgG2型单克隆抗体，通过特异性靶向并结合神经生长因子（NGF）来发挥镇痛作用。其核心机制是阻断NGF与周围神经系统中的TrkA（高亲和力酪氨酸激酶受体）和p75（低亲和力受体）结合，从而抑制因炎症或损伤导致的神经敏

生物活性：Tanezumab (RN-624) is a humanized anti-NGF mAb with high affinity and specificity. Tanezumab blocks NGF binding to its recept