摘要:Gao Y, Jing M, Ge R, Zhou Z, Sun Y. Inhibition of hypoxia inducible factor 1α by siRNA-induced apoptosis in human retinoblastoma
1. Gao Y, Jing M, Ge R, Zhou Z, Sun Y. Inhibition of hypoxia inducible factor 1α by siRNA-induced apoptosis in human retinoblastoma Cells. J Biochem Mol Toxicol. 2014;28(9):394-9.
论文涉及多组图片重复使用的学术不端。
论文中 Figure 5 免疫印迹 Hypoxia 组β-actin 与(Gao Yu 本人, Mol Cell Biochem. 2016; 414(1-2):77-84)中 Figure 5 VCR/IAP-2的β-actin 重复。论文中 Figure 4 流式细胞仪结果 Hypoxia 组与(Gao Yu 本人, Mol Cell Biochem. 2016; 414(1-2):77-84)中流式细胞仪结果重复。
2. Gao Yu, Jing Ming, Ge Rongrong, Lang Lili. Induction of hypoxia-inducible factor-1α by BDNF protects retinoblastoma cells against chemotherapy-induced apoptosis. Mol Cell Biochem. 2016;414(1-2):77-84.
论文涉及严重学术不端,涉及与多篇不相关文章重复,还有文章内部图片重复使用。其中 Figure 2B 免疫印迹的 HIF-1α与其它论文(Min A, Zhu C, Wang J, Peng S, Shuai C, Gao S, Tang Z, Su T. Focal adhesion kinase knockdown in carcinomaassociated fibroblasts inhibits oral squamous cell carcinoma metastasis via downregulating MCP-1/CCL2 expression. J Biochem Mol Toxicol. 2015;29(2):70-6.)中 Figure 1B 中α-SMA 条带重复,同一 figure 中β-actin 与上述论文同一 figure 中β-actin重复;Figure 5 中 CDDP/BDNF 处理的 Knockdown 组 IAP-2 右侧 2 条带与其它论文(Min A, Zhu C, Peng S, Shuai C, Sun L, Han Y, Qian Y, Gao S, Su T. Downregulation of Microrna-148a in Cancer-Associated Fibroblasts from Oral Cancer Promotes Cancer Cell Migration and Invasion by Targeting Wnt10b. J Biochem Mol Toxicol. 2016;30(4):186-91.)Figure 4 的β-actin(NF 组)一致。Figure 4A 中流式细胞仪结果大量重复。
3. Gao Yu, Zhang Hongjun, Zhao Shaofei, He Daotong, Gu Cao. Nanofluorescence Probes to Detect miR-192/Integrin Alpha 1 and Their Correlations with Retinoblastoma. J Biomed Nanotechnol. 2021;17(11):2176-2185.
论文涉及严重学术不端,将同一图片用作不同处理组,甚至是同一种细胞标注为2 种细胞。论文中 Figure 5C 标注的是 RBL-20 细胞,同一图片在 Figure 7B 则标注为RB116 细胞。在 Figure 5 中,同一个细胞的荧光图片(Figure 5G 是 RBL-20 细胞Figure 5L 是 293T 细胞)又用来作为不同细胞,检测不同 miRNA 或分子。同时,Figure 6L 还涉及与其它论文(Comput Math Methods Med. 2022;2022:8388473.)视野(Figure 3c)重复,涉及论文工厂行为。
4. Gu Cao, Zhang Hongjun, Zhao Shaofei, He Daotong, Gao Yu. Mesenchymal Stem Cell Exosomal miR-146a Mediates the Regulation of the TLR4/MyD88/NF-κB Signaling Pathway in Inflammation due to Diabetic Retinopathy. Comput Math
Methods Med. 2022; 2022:3864863.
论文由上海市自然科学基金资助,涉嫌图片重复使用。Figure 7a 中β-actin 与Figure 8a 中β-actin 完全一样,目前已被杂志社撤稿。
5. Gu Cao, Zhang Hongjun, Li Qing, Zhao Shaofei, Gao Yu. MiR-192 attenuates high glucose-induced pyroptosis in retinal pigment epithelial cells via inflammasome modulation. Bioengineered. 2022 Apr;13(4):10362-10372.
该论文涉嫌论文工厂,论文中 Figure 1b 细胞增殖实验,mannitol 处理组 DAPI 及EdU 染色竟然与完全不相干的论文 Figure 8d 细胞增殖实验的 TMAO+si-NEAT1+STAT3重复(Liu A, Zhang Y, Xun S, Sun M. Trimethylamine N-oxide promotes atherosclerosis via regulating the enriched abundant transcript 1/miR-370-3p/signal transducer and activator of transcription 3/flavin-containing monooxygenase-3 axis. Bioengineered. 2022 Jan;13(1):1541-1553.)。
来源:学者探讨