摘要：The food enzyme endo-polygalacturonase ((1-4)-α-d-galacturonan glycanohydrolase, EC 3.2.1.15) is produced with the genetically mod

核心提示：2025年5月12日，欧盟食品安全局就一种食品酶内切多聚半乳糖醛酸酶（endo-polygalacturonase）的安全性评价发布意见。……（世界食品网-www.shijieshipin.com）

2025年5月12日，欧盟食品安全局就一种食品酶内切多聚半乳糖醛酸酶（endo-polygalacturonase）的安全性评价发布意见。
据了解，这种食品酶是由转基因里氏木霉菌株RF6197生产的，旨在用于七种食品生产过程。

经过评估，专家小组得出结论，这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下：

The food enzyme endo-polygalacturonase ((1-4)-α-d-galacturonan glycanohydrolase, EC 3.2.1.15) is produced with the genetically modified Trichoderma reesei strain RF6197 by AB Enzymes GmbH. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in five food manufacturing processes. Subsequently, the applicant has requested to extend its use to include two additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of seven food manufacturing processes. As the food enzyme–total organic solids (TOS) are removed from or not carried into the final foods in three food manufacturing processes, the dietary exposure to the food enzyme–TOS was estimated only for the remaining four processes. The dietary exposure was calculated to be up to 0.137 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1000 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 7299. based on the new data, the revised margin of exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.

来源：食品世界