摘要：近期研究显示，脊髓损伤、多发性硬化症和创伤性脑损伤患者常出现肠道微生物群失衡，可能通过影响免疫和炎症反应影响疾病进程。粪菌移植等疗法有望成为改善疾病症状和预后的新策略。
目前已有肠道微生物群与中枢神经系统疾病关系的研究揭示了脑-肠轴在健康和疾病中的重要性。
近期研究显示，脊髓损伤、多发性硬化症和创伤性脑损伤患者常出现肠道微生物群失衡，可能通过影响免疫和炎症反应影响疾病进程。粪菌移植等疗法有望成为改善疾病症状和预后的新策略。
为此，选择本刊学者2023-2024年发表的帕金森病发病机制的热点综述文章3篇，推荐读者阅读。
(1) Dual-directional regulation of spinal cord injury and the gut microbiota
脊髓损伤与肠道微生物群的双向调控
Yinjie Cui 1, Jingyi Liu 2, Xiao Lei 3, Shuwen Liu 2, Haixia Chen 2, Zhijian Wei 4, Hongru Li 2, Yuan Yang 2, Chenguang Zheng 5, Zhongzheng Li 2
1 Academy of Medical Engineering and Translational Medicine, Tianjin University; School of Medical Technology; Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
2 Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
3 International Cooperation and Exchange Office, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China, India.
4 International Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China; Department of Orthopedics, Qilu Hospital of Shandong University, Jinan, Shandong Province, China.
5 Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
引用本文：
Cui Y, Liu J, Lei X, Liu S, Chen H, Wei Z, Li H, Yang Y, Zheng C, Li Z. Dual-directional regulation of spinal cord injury and the gut microbiota. Neural Regen Res. 2024;19(3):548-556.
正文链接：
(2) Gut flora in multiple sclerosis: implications for pathogenesis and treatment
多发性硬化症中的肠道菌群：对发病机制和治疗的影响
Weiwei Zhang 1, Ying Wang 1, Mingqin Zhu 1, Kangding Liu 1, Hong-Liang Zhang 2
1 Department of Neurology, the First Hospital of Jilin University, Jilin University, Changchun, Jilin Province, China.
2 Department of Life Sciences, National Natural Science Foundation of China, Beijing, China.
引用本文：
Zhang W, Wang Y, Zhu M, Liu K, Zhang HL. Gut flora in multiple sclerosis: implications for pathogenesis and treatment. Neural Regen Res. 2024;19(7):1480-1488.
正文链接：
(3) Gut microbial regulation of innate and adaptive immunity after traumatic brain injury
创伤性脑损伤后肠道微生物对先天性和适应性免疫的调控
Marta Celorrio 1, Kirill Shumilov 1, Stuart H Friess 1
1 Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
引用本文：
Celorrio M, Shumilov K, Friess SH. Gut microbial regulation of innate and adaptive immunity after traumatic brain injury. Neural Regen Res. 2024;19(2):272-276.
正文链接：
来源：中国神经再生研究杂志
